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bioRxiv · 10.1101/2021.09.24.461607

The genomic context for aflatoxin B1-degrading Pseudomonas strains

Tang, J.·Deng, D.·Song, M.·Liu, Z.·Ma, S.·Wang, Y.
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Abstract

The whole genomes of three strains were sequenced and annotated. COG (Clusters of Orthologous Groups) and GO (Gene Ontology) annotations of the protein-coding genes from three strains show a conservation of genome-wide protein functions in genus Pseudomonas. However, the AFB1-degrading strains HAI2 and HT3 harbor much more genes belonged to the pathway of xenobiotics biodegradation and metabolism than non-degrading strain 48. Besides, the enzyme families potentially involved in the AFB1 degradation of bacteria are more abundant in the two AFB1-degrading strains. A pan-genome profile was then formed by comparing the genomes against other reference genomes of the corresponding Pseudomonas species. Accordingly, a total of 1,528 genes were found to be specific in AFB1-degrading strains, and 65 genes of them are related to oxidoreductase activity.

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Tang, J., Deng, D., Song, M., Liu, Z., Ma, S., Wang, Y.. 2021-09-24. The genomic context for aflatoxin B1-degrading Pseudomonas strains. https://doi.org/10.1101/2021.09.24.461607

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