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bioRxiv · 10.1101/2021.09.06.459157

Non-Gaussian, transiently anomalous and ergodic self-diffusion of flexible dumbbells in crowded two-dimensional environments: coupled translational and rotational motions

Abstract

We employ Langevin-dynamics simulations to unveil non-Brownian and non-Gaussian center-of-mass self-diffusion of massive flexible dumbbell-shaped particles in crowded two-dimensional solutions. We also study the intra-dumbbell dynamics due to the relative motion of the two constituent elastically-coupled disks. Our main focus is on effects of the crowding fraction{phi} and the particle structure on the diffusion characteristics. We evaluate the time-averaged mean-squared displacement (TAMSD), the displacement probability-density function (PDF) and the displacement autocorrelation function (ACF) of the dimers. For the TAMSD at highly crowded conditions of dumbbells, e.g., we observe a transition from the short-time ballistic behavior, via an intermediate subdiffusive regime, to long-time Brownian-like spreading dynamics. The crowded system of dimers exhibits two distinct diffusion regimes distinguished by the scaling exponent of the TAMSD, the dependence of the diffusivity on{phi} , and the features of the displacement-ACF. We attribute these regimes to a crowding-induced transition from a viscous to a viscoelastic diffusion medium upon growing{phi} . We also analyze the relative motion in the dimers, finding that larger{phi} suppress their vibrations and yield strongly non-Gaussian PDFs of rotational displacements. For the diffusion coefficients D({phi}) of translational and rotational motion of the dumbbells an exponential decay with{phi} for weak and a power-law D({phi}) {propto} ({phi} -{phi}[*] )2.4 for strong crowding is found. A comparison of simulation results with theoretical predictions for D({phi}) is discussed and some relevant experimental systems are overviewed.

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BibTeXRIS

Klett, K., Cherstvy, A. G., Shin, J., Sokolov, I. M., Metzler, R.. 2021-09-06. Non-Gaussian, transiently anomalous and ergodic self-diffusion of flexible dumbbells in crowded two-dimensional environments: coupled translational and rotational motions. https://doi.org/10.1101/2021.09.06.459157

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