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bioRxiv · 10.1101/2021.07.27.454091

Characterization of a Novel Plasmid in Serratia marcescens Harboring blaGES-5 Isolated from a Nosocomial Outbreak in Japan

Nakanishi, N.·Komatsu, S.·Iwamoto, T.·Nomoto, R.
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Abstract

Serratia marcescens is a nosocomial pathogen with carbapenem resistance, limiting the availability of effective treatment options. In this study, we performed molecular characterization of GES-5 carbapenemase-producing S. marcescens isolated from an outbreak in Japan. Comparative genetic analysis revealed that the blaGES-5-encoding plasmid p2020-O-9 is a unique plasmid contributing towards carbapenem resistance. Furthermore, this study highlights the necessity of surveillance programs for monitoring novel, along with commonly occurring carbapenemases in clinical settings.

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Nakanishi, N., Komatsu, S., Iwamoto, T., Nomoto, R.. 2021-07-28. Characterization of a Novel Plasmid in Serratia marcescens Harboring blaGES-5 Isolated from a Nosocomial Outbreak in Japan. https://doi.org/10.1101/2021.07.27.454091

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