nf-LO: A scalable, containerised workflow for genome-to-genome lift over

Talenti, A.; Prendergast, J.

doi:10.1101/2021.05.25.445595

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bioRxiv · 10.1101/2021.05.25.445595

nf-LO: A scalable, containerised workflow for genome-to-genome lift over

Talenti, A.·Prendergast, J.

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Abstract

The increasing availability of new genome assemblies often comes with an impaired amount of associated genomic annotations, limiting the range of studies that can be performed. A common workaround is to lift over annotations from better annotated genomes. However, generating the files required to perform a liftover is computationally and labour intensive and only a limited number are currently publicly available. Here we present nf-LO (nextflow-LiftOver), a containerised and scalable Nextflow pipeline that enables liftovers within and between any species for which assemblies are available. nf-LO will consequently facilitates data interpretation across a broad range of genomic studies.

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Talenti, A., Prendergast, J.. 2021-05-25. nf-LO: A scalable, containerised workflow for genome-to-genome lift over. https://doi.org/10.1101/2021.05.25.445595

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