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bioRxiv · 10.1101/2021.05.12.443812

A novel cholinergic neural pathway and its role in the drug relapse

He, T.·Chen, W.·Fan, Y.·Xu, X.·Wang, Z.·Li, N.·Guo, H.·Lu, X.·Ge, F.·Guan, X.
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Abstract

The lateral parabrachial nucleus (LPB) is critical hub implicated in the control of food intake, reward and aversion. Here, we identified a novel cholinergic projection from choline acetyltransferase (ChAT)-positive neurons in external portion of the lateral parabrachial nucleus (eLPBChAT) to {gamma}-aminobutyric acid (GABA) neurons in central nucleus of amygdala (CeAGABA), activation of which could block methamphetamine (METH)-primed conditioned place preference (CPP) in mice.

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He, T., Chen, W., Fan, Y., Xu, X., Wang, Z., Li, N., Guo, H., Lu, X., Ge, F., Guan, X.. 2021-05-13. A novel cholinergic neural pathway and its role in the drug relapse. https://doi.org/10.1101/2021.05.12.443812

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