Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees

Yadav, P.; Sapkal, G. N.; Abraham, P.; Ella, R.; Deshpande, G.; Patil, D. Y.; Nyayanit, D.; Gupta, N.; Sahay, R. R.; Shete, A. M.; Panda, S.; Bhargava, B.; Mohan, V. K.

doi:10.1101/2021.04.23.441101

bioRxiv · 10.1101/2021.04.23.441101

Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees

Yadav, P.·Sapkal, G. N.·Abraham, P.·Ella, R.·Deshpande, G.·Patil, D. Y.·Nyayanit, D.·Gupta, N.·Sahay, R. R.·Shete, A. M.·Panda, S.·Bhargava, B.·Mohan, V. K.

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Abstract

The drastic rise in the number of cases in Maharashtra, India has created a matter of concern for public health experts. Twelve isolates of VUI lineage B.1.617 were propagated in VeroCCL81 cells and characterized. Convalescent sera of the COVID-19 cases and recipients of BBV152 (Covaxin) were able to neutralize VUI B.1.617.

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Yadav, P., Sapkal, G. N., Abraham, P., Ella, R., Deshpande, G., Patil, D. Y., Nyayanit, D., Gupta, N., Sahay, R. R., Shete, A. M., Panda, S., Bhargava, B., Mohan, V. K.. 2021-04-23. Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees. https://doi.org/10.1101/2021.04.23.441101

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