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bioRxiv · 10.1101/2021.03.26.437153

Comparison of SARS-CoV-2 VOC 202012/01 (UK variant) and D614G variant transmission by different routes in Syrian hamsters

Mohandas, S.·Yadav, P.·Nyayanit, D.·Shete-Aich, A.·Sarkale, P.·Hundekar, S.·Kumar, S.·Lole, K.
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Abstract

Many SARS-CoV-2 variants of concern has been reported recently which were linked to increased transmission. In our earlier study on virus shedding using VOC 202012/01(UK variant) and D614G variant in hamster model, we observed significantly higher viral RNA shedding through nasal wash in case of UK variant. Hence, we compared the transmission of both the UK and D614G variant by various routes in Syrian hamsters to understand whether the high viral RNA shedding could enhance the transmission efficiency of the variant. The current study demonstrated comparable transmission efficiency of both UK and D614G variants of SARS-CoV-2 in Syrian hamsters.

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Mohandas, S., Yadav, P., Nyayanit, D., Shete-Aich, A., Sarkale, P., Hundekar, S., Kumar, S., Lole, K.. 2021-03-26. Comparison of SARS-CoV-2 VOC 202012/01 (UK variant) and D614G variant transmission by different routes in Syrian hamsters. https://doi.org/10.1101/2021.03.26.437153

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