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bioRxiv · 10.1101/2021.03.11.434452

Value signals in orbitofrontal cortex predict economic decisions on a trial-to-trial basis

McGinty, V. B.·Lupkin, S. M.
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Abstract

The primate orbitofrontal cortex (OFC) has long been recognized for its role in value-based decisions; however, the exact mechanism linking OFC value representations to decision outcomes has remained elusive. To address this question we show for the first time that trial-wise variability in choices can be explained by variability in value signals decoded from many simultaneously recorded OFC neurons. Mechanistically, this relationship is consistent with the projection of activity within a low-dimensional value-encoding subspace onto a potentially higher-dimensional, behaviorally-potent output subspace.

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McGinty, V. B., Lupkin, S. M.. 2021-03-12. Value signals in orbitofrontal cortex predict economic decisions on a trial-to-trial basis. https://doi.org/10.1101/2021.03.11.434452

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