Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes

Jolly, B.; Rophina, M.; Shamnath, A.; Imran, M.; Bhoyar, R. C.; Divakar, M. K.; Rani, P. R.; Ranjan, G.; Sehgal, P.; Chandrasekhar, P.; Afsar, S.; Lakshmi, J. V.; Surekha, A.; Sivasubbu, S.; Scaria, V.

doi:10.1101/2020.12.24.424332

bioRxiv · 10.1101/2020.12.24.424332

Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes

Jolly, B.·Rophina, M.·Shamnath, A.·Imran, M.·Bhoyar, R. C.·Divakar, M. K.·Rani, P. R.·Ranjan, G.·Sehgal, P.·Chandrasekhar, P.·Afsar, S.·Lakshmi, J. V.·Surekha, A.·Sivasubbu, S.·Scaria, V.

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Abstract

Many antibody and immune escape variants in SARS-CoV-2 are now documented in literature. The availability of SARS-CoV-2 genome sequences enabled us to investigate the occurrence and genetic epidemiology of the variants globally. Our analysis suggests that a number of genetic variants associated with immune escape have emerged in global populations.

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Jolly, B., Rophina, M., Shamnath, A., Imran, M., Bhoyar, R. C., Divakar, M. K., Rani, P. R., Ranjan, G., Sehgal, P., Chandrasekhar, P., Afsar, S., Lakshmi, J. V., Surekha, A., Sivasubbu, S., Scaria, V.. 2020-12-26. Genetic epidemiology of variants associated with immune escape from global SARS-CoV-2 genomes. https://doi.org/10.1101/2020.12.24.424332

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