Experimental SARS-CoV-2 infection of bank voles - general susceptibility but lack of direct transmission

Ulrich, L.; Michelitsch, A.; Halwe, N.; Wernike, K.; Hoffmann, D.; Beer, M.

doi:10.1101/2020.12.24.424203

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bioRxiv · 10.1101/2020.12.24.424203

Experimental SARS-CoV-2 infection of bank voles - general susceptibility but lack of direct transmission

Ulrich, L.·Michelitsch, A.·Halwe, N.·Wernike, K.·Hoffmann, D.·Beer, M.

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Abstract

After experimental inoculation, SARS-CoV-2 infection was proven for bank voles by seroconversion within eight days and detection of viral RNA in nasal tissue for up to 21 days. However, transmission to contact animals was not detected. Therefore, bank voles are unlikely to establish effective SARS-CoV-2 transmission cycles in nature. Article Summary LineBank voles show low-level viral replication and seroconversion upon infection with SARS-CoV-2, but lack transmission to contact animals.

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Ulrich, L., Michelitsch, A., Halwe, N., Wernike, K., Hoffmann, D., Beer, M.. 2020-12-24. Experimental SARS-CoV-2 infection of bank voles - general susceptibility but lack of direct transmission. https://doi.org/10.1101/2020.12.24.424203

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