Computational study of the effect of hypoxia on cancer response to radiation treatment

Muntean, A.; Korhonen, T.; Lagerlöf, J. H.

doi:10.1101/2020.10.21.348474

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bioRxiv · 10.1101/2020.10.21.348474

Computational study of the effect of hypoxia on cancer response to radiation treatment

Muntean, A.·Korhonen, T.·Lagerlöf, J. H.

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Abstract

We perform a computational study of the propagation of the oxygen concentration within a two-dimensional slice of a heterogeneous tumour region where the position and shape of the blood vessels are known. Exploiting the parameters space, we explore which effect is noticeable what concerns the formation of hypoxic zones. We use this information to anticipate a patient-specific radiation treatment with controlled response of the cancer growth.

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Muntean, A., Korhonen, T., Lagerlöf, J. H.. 2020-10-21. Computational study of the effect of hypoxia on cancer response to radiation treatment. https://doi.org/10.1101/2020.10.21.348474

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