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bioRxiv · 10.1101/2020.10.14.338418

SM-Omics: An automated platform for high-throughput spatial multi-omics

Vickovic, S.·Loetstedt, B.·Klughammer, J.·Segerstolpe, A.·Rozenblatt-Rosen, O.·Regev, A.
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Abstract

The spatial organization of cells and molecules plays a key role in tissue function in homeostasis and disease. Spatial Transcriptomics (ST) has recently emerged as a key technique to capture and positionally barcode RNAs directly in tissues. Here, we advance the application of ST at scale, by presenting Spatial Multiomics (SM-Omics) as a fully automated high-throughput platform for combined and spatially resolved transcriptomics and antibody-based proteomics.

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Vickovic, S., Loetstedt, B., Klughammer, J., Segerstolpe, A., Rozenblatt-Rosen, O., Regev, A.. 2020-10-15. SM-Omics: An automated platform for high-throughput spatial multi-omics. https://doi.org/10.1101/2020.10.14.338418

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