Impact of COVID-19 on Hospital Admission of Acute Stroke patients in Bangladesh

Hasan, A. T. M. H.; Das, S. C.; Islam, M. S.; Mansur, M.; Shawon, M. S. R.; Hassan, R.; Chowdhury, M. S. J. H.; Mondal, M. B. A.; Mohammad, Q. D.

doi:10.1101/2020.09.28.316448

bioRxiv · 10.1101/2020.09.28.316448

Impact of COVID-19 on Hospital Admission of Acute Stroke patients in Bangladesh

Hasan, A. T. M. H.·Das, S. C.·Islam, M. S.·Mansur, M.·Shawon, M. S. R.·Hassan, R.·Chowdhury, M. S. J. H.·Mondal, M. B. A.·Mohammad, Q. D.

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Abstract

BackgroundWith the proposed pathophysiologic mechanism of neurologic injury by SARS COV-2 the frequency of stroke and henceforth the related hospital admissions were expected to rise. In this paper we investigate this presumption by comparing the frequency of admissions of stroke cases in Bangladesh before and during the pandemic. MethodsWe conducted a retrospective analysis of stroke admissions in a 100-bed stroke unit at the National Institute of Neurosciences and Hospital (NINS&H) which is considerably a large stroke unit. We considered all the admitted cases from the 1st January to the 30th June, 2020. We used Poisson regressions to determine whether statistically significant changes in admission counts can be found before and after 25 March since when there is a surge in COVID-19 infections. ResultsA total of 1394 stroke patients got admitted during the study period. Half of the patients were older than 60 years, whereas only 2.6% were 30 years old or younger with a male-female ratio of 1.06:1. From January to March, 2020 the mean rate of admission was 302.3 cases per month which dropped to 162.3 cases per month from April to June with an overall reduction of 46.3% in acute stroke admission per month. In those two periods, reductions in average admission per month for ischemic stroke (IST), intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH) and venous stroke (VS) were 45.5%, 37.2%, 71.4% and 39.0%, respectively. Based on weekly data, results of Poisson regressions confirm that the average number of admissions per week dropped significantly during the last three months of the sample period. Further, in the first three months, a total of 22 cases of hyperacute stroke management were done whereas in the last three months there was an 86.4% reduction in the number of hyperacute stroke patients getting reperfusion treatment. Only 38 patients (2.7%) were later found to be RT- PCR for SARS Cov-2 positive based on nasal swab testing. ConclusionOur study revealed more than fifty percent reduction in acute stroke admission during the COVID-19 pandemic. It is still elusive whether the reduction is related to the fear of getting infected by COVID-19 from hospitalization or the overall restriction on public movement and stay-home measures.

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Hasan, A. T. M. H., Das, S. C., Islam, M. S., Mansur, M., Shawon, M. S. R., Hassan, R., Chowdhury, M. S. J. H., Mondal, M. B. A., Mohammad, Q. D.. 2020-09-28. Impact of COVID-19 on Hospital Admission of Acute Stroke patients in Bangladesh. https://doi.org/10.1101/2020.09.28.316448

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