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bioRxiv · 10.1101/2020.09.10.291583

Chronically implantable LED arrays for behavioral optogenetics in primates.

Rajalingham, R.·Sorenson, M.·Azadi, R.·Bohn, S.·DiCarlo, J. J.·Afraz, A.
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Abstract

Challenges in behavioral optogenetics in large brains demand development of a chronically implantable platform for light delivery. We have developed Opto-Array, a chronically implantable array of LEDs for high-throughput optogenetic perturbation in non-human primates. We tested the Opto-Array in the primary visual cortex of a macaque monkey, and demonstrated that optogenetic cortical silencing by the Opto-Array results in reliable retinotopic visual deficits on a luminance discrimination task.

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Rajalingham, R., Sorenson, M., Azadi, R., Bohn, S., DiCarlo, J. J., Afraz, A.. 2020-09-11. Chronically implantable LED arrays for behavioral optogenetics in primates.. https://doi.org/10.1101/2020.09.10.291583

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