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bioRxiv · 10.1101/2020.08.29.273755

Size Effect on Structure and Stiffness of Viral DNA during Temperature Variation

Zhang, C.-Y.·Zhang, N.-H.
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Abstract

Structure and stiffness of nucleic acids are closely related to viral infectivity. The article is aimed to clarify a recent controversy on structure variation of viral DNA in temperature-dependent experiments. A multi-scale correlation between microscopic structure of viral DNA and its bulk stiffness is formulated by presenting a two-zone mesoscopic free energy model. Results reveal that the increasing temperature promotes DNA structure transformation from order to disorder, and leads to size effect on temperature-dependency of stiffness and structure of viral DNA.

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Zhang, C.-Y., Zhang, N.-H.. 2020-08-31. Size Effect on Structure and Stiffness of Viral DNA during Temperature Variation. https://doi.org/10.1101/2020.08.29.273755

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