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bioRxiv · 10.1101/2020.08.28.273094

Pocket MUSE: an affordable, versatile and high performance fluorescence microscope using a smartphone

Liu, Y.·Rollins, A. M.·Levenson, R. M.·Fereidouni, F.·Jenkins, M. W.
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Abstract

Smartphone microscopes can be effective tools for a broad range of imaging applications. In this manuscript, we demonstrate the first practical implementation of Microscopy with Ultraviolet Surface Excitation (MUSE) in a compact smartphone microscope called Pocket MUSE, resulting in a remarkably effective design. Fabricated with parts from consumer electronics that are readily available at low cost, the small optical module attaches directly over the rear lens in a smartphone and enables high quality multichannel fluorescence microscopy with submicron resolution over a 10X equivalent field of view. In addition to the novel optical configuration, Pocket MUSE is compatible with a series of simple, portable and user-friendly sample preparation strategies that can be directly implemented for various microscopy applications for point-of-care diagnostics, at-home health monitoring, plant biology, STEM education, environmental studies, etc.

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Liu, Y., Rollins, A. M., Levenson, R. M., Fereidouni, F., Jenkins, M. W.. 2020-08-31. Pocket MUSE: an affordable, versatile and high performance fluorescence microscope using a smartphone. https://doi.org/10.1101/2020.08.28.273094

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