Loss of integration of brain netwroks after one night of sleep deprivation underlies worsening of attentive functions

Pesoli, M.; Rucco, R.; Liparoti, M.; Lardone, A.; D'Aurizio, G.; Minino, R.; Troisi Lopez, E.; Paccone, A.; Granata, C.; Mandolesi, L.; Sorrentino, G.; Sorrentino, P.

doi:10.1101/2020.07.15.197590

bioRxiv · 10.1101/2020.07.15.197590

Loss of integration of brain netwroks after one night of sleep deprivation underlies worsening of attentive functions

Pesoli, M.·Rucco, R.·Liparoti, M.·Lardone, A.·D'Aurizio, G.·Minino, R.·Troisi Lopez, E.·Paccone, A.·Granata, C.·Mandolesi, L.·Sorrentino, G.·Sorrentino, P.

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Abstract

The topology of brain networks changes according to environmental demands and can be described within the framework of graph theory. We hypothesized that 24-hours long sleep deprivation (SD) causes functional rearrangements of the brain topology so as to impair optimal communication, and that such rearrangements relate to the performance in specific cognitive tasks, namely the ones specifically requiring attention. Thirty-two young men underwent resting-state MEG recording and assessments of attention and switching abilities before and after SD. We found loss of integration of brain network and a worsening of attention but not of switching abilities. These results show that brain network changes due to SD affect switching abilities, worsened attention and induce large-scale rearrangements in the functional networks.

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Pesoli, M., Rucco, R., Liparoti, M., Lardone, A., D'Aurizio, G., Minino, R., Troisi Lopez, E., Paccone, A., Granata, C., Mandolesi, L., Sorrentino, G., Sorrentino, P.. 2020-07-17. Loss of integration of brain netwroks after one night of sleep deprivation underlies worsening of attentive functions. https://doi.org/10.1101/2020.07.15.197590

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