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bioRxiv · 10.1101/2020.06.21.163485

LATER but FORTIOR: diffusion modelling of inhibition of return

Abstract

Inhibition of return (IOR) refers to the slowing of response times (RTs) for stimuli repeated at previously inspected locations, as compared with novel ones. However, the exact processing stage(s) at which IOR occurs, and its nature across different response modalities, remain debated. We tested predictions on these issues originating from the FORTIOR model (fronto-parietal organization of response times in IOR; Seidel Malkinson & Bartolomeo, 2018), and from evidence accumulation models. We reanalysed RT data from a target-target IOR paradigm (Bourgeois et al.,2013a, 2013b) by using a LATER-like evidence accumulation model (Carpenter & Williams, 1995), to test the predictions of FORTIOR, and specifically whether IOR could occur at sensory/attentional stages of processing, or at stages of decision and action selection. We considered the following conditions: manual or saccadic response modality, before or after TMS perturbation over four cortical regions. Results showed that the Gaussian noise parameter best explained both manual and saccadic IOR, suggesting that in both response modalities IOR may result from slower accumulation of evidence for repeated locations. Additionally, across stimulated regions, TMS affected only manual RTs, lowering them equally in the conditions with repeated targets (Return) and non-repeated targets (Non-return). Accordingly, the modelling results show that TMS stimulation did not significantly alter the pattern between model parameters, with the Gaussian noise parameter remaining the parameter best explaining the Return - Non-return RT difference. Moreover, TMS over the right intra-parietal sulcus (IPS) perturbed IOR by shortening the Return RT. When directly testing this effect by modelling the TMS impact in the Return condition, the Bayesian information criterion of the Gaussian noise parameter was the smallest, but this effect did not reach significance. These results support the hypothesis that target-target IOR is a predominantly sensory/attentional phenomenon, and may be modulated by activity in fronto-parietal networks.

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BibTeXRIS

Seidel Malkinson, T., Bourgeois, A., Wattiez, N., Pouget, P., Bartolomeo, P.. 2020-06-22. LATER but FORTIOR: diffusion modelling of inhibition of return. https://doi.org/10.1101/2020.06.21.163485

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