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bioRxiv · 10.1101/2020.03.11.987958

A human monoclonal 1 antibody blocking SARS-CoV-2 infection

Wang, C.·Li, W.·Drabek, D.·Okba, N. M. A.·van Haperen, R.·Osterhaus, A. D. M. E.·van Kuppeveld, F. J. M.·Haagmans, B. L.·Grosveld, F.·Bosch, B.-J.
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Abstract

The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV). This cross-neutralizing antibody targets a communal epitope on these viruses and offers potential for prevention and treatment of COVID-19.

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Wang, C., Li, W., Drabek, D., Okba, N. M. A., van Haperen, R., Osterhaus, A. D. M. E., van Kuppeveld, F. J. M., Haagmans, B. L., Grosveld, F., Bosch, B.-J.. 2020-03-12. A human monoclonal 1 antibody blocking SARS-CoV-2 infection. https://doi.org/10.1101/2020.03.11.987958

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