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bioRxiv · 10.1101/2020.02.29.965418

The within-host viral kinetics of SARS-CoV-2

Li, C.·Jinhu, X.·Liu, J.·Zhou, Y.
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Abstract

In this work, we use a within-host viral dynamic model to describe the SARS-CoV-2 kinetics in host. Chest radiograph score data are used to estimate the parameters of that model. Our result shows that the basic reproductive number of SARS-CoV-2 in host growth is around 3.79. Using the same method we also estimate the basic reproductive number of MERS virus is 8.16 which is higher than SARS-CoV-2. The PRCC method is used to analyze the sensitivities of model parameters and the drug effects on virus growth are also implemented to analyze the model.

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Li, C., Jinhu, X., Liu, J., Zhou, Y.. 2020-03-02. The within-host viral kinetics of SARS-CoV-2. https://doi.org/10.1101/2020.02.29.965418

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