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bioRxiv · 10.1101/2020.01.15.907733

A minimum reporting standard for multiple sequence alignments

Wong, T. K.·Kalyaanamoorthy, S.·Meusemann, K.·Yeates, D. K.·Misof, B.·Jermiin, L. S.
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Abstract

Multiple sequence alignments (MSAs) play a pivotal role in studies of molecular sequence data, but nobody has developed a minimum reporting standard (MRS) to quantify the completeness of MSAs in terms of completely-specified nucleotides or amino acids. We present an MRS that relies on four simple completeness metrics. The metrics are implemented in AliStat, a program developed to support the MRS. A survey of published MSAs illustrates the benefits and unprecedented transparency offered by the MRS.

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Wong, T. K., Kalyaanamoorthy, S., Meusemann, K., Yeates, D. K., Misof, B., Jermiin, L. S.. 2020-01-15. A minimum reporting standard for multiple sequence alignments. https://doi.org/10.1101/2020.01.15.907733

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