Oasis2.0: improved online analysis of small RNA-seq data

Rahman, R.-U.; Gautam, A.; Bethune, J.; Sattar, A.; Fiosins, M.; Magruder, D. S.; Capece, V.; Shomroni, O.; Bonn, S.

doi:10.1101/170738

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bioRxiv · 10.1101/170738

Oasis2.0: improved online analysis of small RNA-seq data

Rahman, R.-U.·Gautam, A.·Bethune, J.·Sattar, A.·Fiosins, M.·Magruder, D. S.·Capece, V.·Shomroni, O.·Bonn, S.

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Abstract

Oasis 2 is a new main release of the Oasis web application for the detection, differential expression, and classification of small RNAs in deep sequencing data. Compared to its predecessor Oasis, Oasis 2 features a novel and speed-optimized sRNA detection module that supports the identification of small RNAs in any organism with higher accuracy. Next to the improved detection of small RNAs in a target organism, the software now also recognizes potential cross-species miRNAs and viral and bacterial sRNAs in infected samples. In addition, novel miRNAs can now be queried and visualized interactively, providing essential information for over 700 high-quality miRNA predictions across 14 organisms. Robust biomarker signatures can now be obtained using the novel enhanced classification module. Oasis 2 enables biologists and medical researchers to rapidly analyze and query small RNA deep sequencing data with improved precision, recall, and speed, in an interactive and user-friendly environment.\n\nAvailability and Implementation: Oasis 2 is implemented in Java, J2EE, mysql, Python, R, PHP and JavaScript. It is freely available at http://oasis.dzne.de

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Rahman, R.-U., Gautam, A., Bethune, J., Sattar, A., Fiosins, M., Magruder, D. S., Capece, V., Shomroni, O., Bonn, S.. 2017-08-01. Oasis2.0: improved online analysis of small RNA-seq data. https://doi.org/10.1101/170738

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