Fibroblasts cell lines misclassified as cancer cell lines

de Weck, A.; Bitter, H.; Kauffmann, A.

doi:10.1101/166199

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bioRxiv · 10.1101/166199

Fibroblasts cell lines misclassified as cancer cell lines

de Weck, A.·Bitter, H.·Kauffmann, A.

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Abstract

Large collections of immortalized cancer cell lines have been widely used as model systems for cancer research and drug discovery. Some of these models however display more fibroblast-like than cancer-like characteristics based on their genetic and genomic characterization. The correct annotation of these cell lines remains a challenge. Here, we report the outcome of our analysis on a large cancer cell line collection, where we found a subset of cell lines misclassified.

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de Weck, A., Bitter, H., Kauffmann, A.. 2017-07-20. Fibroblasts cell lines misclassified as cancer cell lines. https://doi.org/10.1101/166199

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