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bioRxiv · 10.1101/100248

Repression of YdaS Toxin is Mediated by Transcriptional Repressor RacR in the cryptic rac prophage of Escherichia coli K12

Krishnamurthi, R.·Ghosh, S.·Khedkar, S.·Seshasayee, A. S. N.
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Abstract

AbstractHorizontal gene transfer is a major driving force behind the genomic diversity seen in prokaryotes. The rac prophage in E.coli K12 encodes a putative transcription factor RacR, whose deletion is lethal. We have shown that the essentiality of racR in E.coli K12 is attributed to its role in transcriptionally repressing a toxin gene called ydaS, which is coded adjacent and divergently to racR.

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Krishnamurthi, R., Ghosh, S., Khedkar, S., Seshasayee, A. S. N.. 2017-01-13. Repression of YdaS Toxin is Mediated by Transcriptional Repressor RacR in the cryptic rac prophage of Escherichia coli K12. https://doi.org/10.1101/100248

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