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bioRxiv · 10.1101/087932

biMM: Efficient estimation of genetic variances andcovariances for cohorts with high-dimensional phenotype measurements

Pirinen, M.·Benner, C.·Marttinen, P.·Jarvelin, M.-R.·Rivas, M. A.·Ripatti, S.
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Abstract

Genetic research utilizes a decomposition of trait variances and covariances into genetic and environmental parts. Our software package biMM is a computationally efficient implementation of a bivariate linear mixed model for settings where hundreds of traits have been measured on partially overlapping sets of individuals.\n\nAvailabilityImplementation in R freely available at www.iki.fi/mpirinen.

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Pirinen, M., Benner, C., Marttinen, P., Jarvelin, M.-R., Rivas, M. A., Ripatti, S.. 2016-11-15. biMM: Efficient estimation of genetic variances andcovariances for cohorts with high-dimensional phenotype measurements. https://doi.org/10.1101/087932

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