Assessing Prediction Performance of Neoadjuvant Chemotherapy Response in Bladder Cancer

Chris Cremer

doi:10.1101/075705

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bioRxiv · 10.1101/075705

Assessing Prediction Performance of Neoadjuvant Chemotherapy Response in Bladder Cancer

Chris Cremer

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Abstract

Neoadjuvant chemotherapy is a treatment routinely prescribed to patients diagnosed with muscle-invasive bladder cancer. Unfortunately, not all patients are responsive to this treatment and would greatly benefit from an accurate prediction of their expected response to chemotherapy. In this project, I attempt to develop a model that will predict response using tumour microarray data. I show that using my dataset, every method is insufficient at accurately classifying responders and non-responders.

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Chris Cremer. 2016-09-16. Assessing Prediction Performance of Neoadjuvant Chemotherapy Response in Bladder Cancer. https://doi.org/10.1101/075705

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