PathScore: a web tool for identifying altered pathways in cancer data

Stephen G Gaffney; Jeffrey P. Townsend

doi:10.1101/067090

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bioRxiv · 10.1101/067090

PathScore: a web tool for identifying altered pathways in cancer data

Stephen G Gaffney·Jeffrey P. Townsend

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Abstract

SummaryPathScore quantifies the level of enrichment of somatic mutations within curated pathways, applying a novel approach that identifies pathways enriched across patients. The application provides several user-friendly, interactive graphic interfaces for data exploration, including tools for comparing pathway effect sizes, significance, gene-set overlap and enrichment differences between projects.\n\nAvailability and ImplementationWeb application available at pathscore.publichealth.yale.edu. Site implemented in Python and MySQL, with all major browsers supported. Source code available at github.com/sggaffney/pathscore with a GPLv3 license.\n\nContactstephen.gaffney@yale.edu\n\nSupplementary InformationAdditional documentation can be found at http://pathscore.publichealth.yale.edu/faq.

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Stephen G Gaffney, Jeffrey P. Townsend. 2016-08-01. PathScore: a web tool for identifying altered pathways in cancer data. https://doi.org/10.1101/067090

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