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bioRxiv · 10.1101/029108

Multi-Unit Activity contains information about spatial stimulus structure in mouse primary visual cortex

Marie Tolkiehn·Simon Schultz
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Abstract

This study investigates the spatial and directional tuning of Multi-Unit Activity (MUA) in mouse primary visual cortex and how MUA can reflect spatiotemporal structures contained in moving gratings. Analysis of multi-shank laminar electrophysiological recordings from mouse primary visual cortex indicates a directional preference for moving gratings around 180{degrees}, while preferred spatial frequency peaks around 0.02 cycles per degree, which is similar as reported in single-unit studies. Using only features from MUA, we further achieved a significant performance in decoding spatial frequency or direction of moving gratings, with average decoding performances of up to 58.54% for 8 directions, and 44% correctly identified spatial frequencies against chance level of 16.7%.

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Marie Tolkiehn, Simon Schultz. 2015-10-14. Multi-Unit Activity contains information about spatial stimulus structure in mouse primary visual cortex. https://doi.org/10.1101/029108

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