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bioRxiv · 10.1101/005082

diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals

Paula Tataru·Jasmine A. Nirody·Yun S. Song
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Abstract

Summary: We present a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. Our method builds on a recent demographic inference method based on the coalescent with recombination, and is able to incorporate demographic information as a prior. Simulation study shows that diCal-IBD has significantly higher recall and precision than that of existing IBD detection methods, while retaining reasonable accuracy for IBD tracts as small as 0.1 cM.\n\nAvailability: http://sourceforge.net/p/dical-ibd\n\nContact: yss@eecs.berkeley.edu

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Paula Tataru, Jasmine A. Nirody, Yun S. Song. 2014-05-12. diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals. https://doi.org/10.1101/005082

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