TY - RPRT TI - Topology-aware thermodynamics for DNA probe design under fixed stringency: Retained paired boxes link mismatch placement, nearest-neighbor stability and room-temperature diagnostic specificity AU - Brukner, I. AU - Krajinovic, M. PY - 2026 DO - 10.64898/2026.06.10.731169 UR - https://www.biorxiv.org/content/10.64898/2026.06.10.731169v1 ID - 10.64898/2026.06.10.731169 ER -