TY - RPRT TI - PARP1 catalytic domain mutations drive high-level resistance to saruparib while preserving DNA damage response vulnerabilities AU - Jordan, M. R. AU - Kersey, J. L. AU - Garrett, J. E. AU - Liu, S. AU - Wan, J. AU - Turchi, J. J. PY - 2026 DO - 10.64898/2026.05.08.723870 UR - https://www.biorxiv.org/content/10.64898/2026.05.08.723870v1 ID - 10.64898/2026.05.08.723870 ER -