TY - RPRT TI - Bio-orthogonal chemistry-based conjugation strategy facilitates investigation of impacts of s2U, s4U, m1A and m6A guide RNA modifications on CRISPR activity. AU - Hoy, A. AU - Zheng, Y. Y. AU - Sheng, j. AU - Royzen, M. PY - 2022 DO - 10.1101/2022.06.09.495561 UR - https://www.biorxiv.org/content/10.1101/2022.06.09.495561v1 ID - 10.1101/2022.06.09.495561 ER -