Improved metagenomic analysis with Kraken 2
Although Krakens k-mer-based approach provides fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed five-fold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis.
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