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Rutledge, S. M.

Publications and source records attributed to Rutledge, S. M..

2 recordsLinked to original sources

Enriching hippocampal memory function in older adults through video games

Healthy aging is accompanied by a steady cognitive decline with clear losses in memory. Animal studies have consistently demonstrated that simply modifying an animals living environment (known as environmental enrichment) can have a positive influence on age-related cognitive decline in the hippocampus. Previously, we showed that playing immersive 3D video games can improve hippocampal-based memory in young healthy adults, suggesting that the exploration of the large open worlds of modern-day video games may act as proxy for environmental enrichment in humans. Here, we replicated our previous video game study in older adults and showing that playing video games for 4 weeks can improve hippocampal-based memory in a population that is already experiencing age-related decline in this memory. Furthermore, we showed that the improvements last for up to 4 weeks past the intervention, highlighting the potential of video games as intervention for age-related cognitive decline.

neuroscience

Enriching hippocampal memory function in older adults through real-world exploration

Age-related structural and functional changes in the hippocampus can have a severe impact on hippocampally-dependent memory performance. Here we test the hypothesis that a real-world spatial exploration intervention will improve hippocampally-dependent memory performance in healthy older adults. We found that following our intervention, participants lure discrimination index (LDI) was significantly higher than it was at baseline, while traditional recognition scores remained relatively unchanged. These results point to the viability of a spatial exploration intervention for improving hippocampally-dependent memory in older adults.

neuroscience