Biology subjects

Prabha, R.

Publications and source records attributed to Prabha, R..

2 recordsLinked to original sources

bioRxiv2025

Tomato Omics Research: Mapping Bibliometric Footprints of Global Research Trends, Collaboration Networks, and Impact Trajectories

Tomato is a globally vital crop and model system for fleshy fruit development, with profound agricultural and economic significance. Omics-based tomato research has revolutionized understanding of fruit quality traits, disease resistance mechanisms, and stress tolerance pathways reflecting insights for breeding innovations to address food security challenges. This bibliometric analysis on tomato omics delivered crucial insights into the evolution and impact of tomato omics research over two decades. Examining 1,702 Scopus-indexed publications, we have shown a remarkable acceleration in research output after 2017, signifying the fields growing significance. Our findings revealed that Biochemistry, Genetics and Molecular Biology dominated the landscape with 1,054 publications, establishing the molecular foundation for tomato research. It identified key global research hubs, with the United States (450 publications) leading, followed by China (310) and Italy (171), while mapping eight distinct International collaboration networks that drive innovation. Through citation analysis, we have pinpointed transformative contributions in microRNA research and genome sequencing, with the fields most influential paper garnering 2,570 citations. Co-authorship network visualization exposed 25 research clusters among 8,103 authors, highlighting prolific contributors including Fernie A.R. (39 publications) and Lucini L. (26). The keyword co-occurrence mapping revealed critical research priorities centered on stress responses, fruit quality, and plant immunity, with "Frontiers in Plant Science" emerging as the fields premier publication venue (92 articles). Our analysis provided a roadmap of tomato omics research progression, offering strategic value for prioritization, collaboration development, and funding allocation to address pressing challenges in global food security and crop improvement.

plant biology↗

bioRxiv2025

Comparative proteomics uncovers distinct biomarkers, protein networks and defense responses in tomato during beneficial and pathogenic microbial interactions

The molecular mechanisms underlying plant responses to beneficial and pathogenic microbial interactions has been uncovered in tomato at the proteomic level. Our study employed LC-MS- based proteomics to investigate differential protein regulation in tomato plants during interactions with beneficial bacteria (Bacillus subtilis BV7) versus pathogenic fungus (Alternaria solani). Comparative analysis revealed distinct protein signatures characterizing each interaction: 232 unique proteins in BV7-treated plants versus 96 in pathogen-infected plants, with 54 proteins shared between treatments. BV7 inoculation enhanced proteins involved in photosynthesis and primary metabolism, with PSI-K emerging as the top biomarker (score 2.53), while pathogen infection triggered focused defense responses with Cytochrome b559 (score 2.38) as the key biomarker. Metabolic pathway analysis demonstrated that BV7 uniquely enhanced vitamin metabolism (thiamine, riboflavin, folate) and energy production pathways, while pathogen infection activated defense-related phenylpropanoid biosynthesis. Analysis of defense enzymes showed pathogen infection induced highest activities of PAL (39.4{+/-}0.46 U h-1 g-1 fw), SOD (29.9{+/-}0.94 U mg-1 protein), POD (3.18{+/-}0.07 g g-1 fw min-1), APx (15.58{+/-}0.23 U mg-1 protein), and GPx (71.51{+/-}0.7 U mg-1 protein), while BV7 maintained moderate enzyme levels, suggesting balanced growth-defense responses. The shared proteins between treatments indicate a common molecular framework potentially contributing to induced systemic resistance. These findings provide novel insights into plant-microbe interactions at the molecular level, identifying specific protein biomarkers and metabolic pathways that could be targeted for enhancing crop productivity and disease resistance. The results have significant implications for developing biological control strategies and improving sustainable agricultural practices.

plant biology↗