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Mougkogiannis, P.

Publications and source records attributed to Mougkogiannis, P..

3 recordsLinked to original sources

On interaction of proteinoids with simulated neural networks

Proteinoids are thermal proteins which swell into microspheres in solution. The proteinoid microspheres show spiking of electrical potential similar to that to that of living neurons. Rich spectrum of proteinoids spiking responses to optical and electrical stimulation makes them promising candidates for neuromorphic unconventional computing devices. We decided to evaluate neuron-like activity of proteinoids in the experimental setups of their interaction with simulate neuronal network of Izhikevich neurons. The simulated neural networks stimulate and modulate electrical activity of proteinoid ensembles by interacting with them via arbitrary form programmable function generator. Different amino-acid compositions of proteinoids responded uniquely to input spiking from simulated neurons. We demonstrated that patterns of electrical spiking activity of proteinoids and complexity of the activity can be tuned by patterns of spikes generated by simulated neurons. The research opens novel venues to establishing interacting between nanobrains - brain-like organoids made from molecules, not animal cells -- and real nervous systems.

biophysics↗

Recognition of sounds by ensembles of proteinoids

Proteinoids are artificial polymers that imitate certain characteristics of natural proteins, including self-organization, catalytic activity, and responsiveness to external stimuli. This paper investigates the potential of proteinoids as organic audio signal processors. We convert sounds of English alphabet into waveforms of electrical potential, feed the waveforms into proteinoid solutions and record electrical responses of the proteinoids. We also undertake a detailed comparison of proteinoids electrical responses (frequencies, periods, and amplitudes) with original input signals. We found that responses of proteinoids are less regular, lower dominant frequency, wider distribution of proteinoids and less skewed distribution of amplitudes compared with input signals. We found that letter of English alphabet uniquely maps onto a pattern of electrical activity of a proteinoid ensemble, that is the proteinoid ensembles recognise spoken letters of English alphabet. The finding will be used in further designs of organic electronic devices, based on ensembles of proteinoids, for sound processing and speech recognition.

biophysics↗

Electrical spiking activity of proteinoids-ZnO colloids

We are studying the remarkable electrical properties of Proteinoids-ZnO micro-spheres with the aim of exploring their potential for a new form of computing. Our research has revealed that these microspheres exhibit behavior similar to neurons, generating electrical spikes that resemble action potentials. Through our investigations, we have studied the underlying mechanism behind this electrical activity and proposed that the spikes arise from oscillations between the degradation and reorganization of proteinoid molecules on the surface of ZnO. These findings offer valuable insights into the potential use of Proteinoids-ZnO colloids in unconventional computing and the development of novel neuromorphic liquid circuits.

biophysics↗