Manjunath, M. | bioRxiv Science

bioRxiv2018

SequencEnG: an Interactive Knowledge Base of Sequencing Techniques

Next-generation sequencing (NGS) techniques are revolutionizing biomedical research by providing powerful methods for generating genomic and epigenomic profiles. The rapid progress is posing an acute challenge to students and researchers to stay acquainted with the numerous available methods. We have developed an interactive online educational resource called SequencEnG (acronym for Sequencing Techniques Engine for Genomics) to provide a tree-structured knowledge base of 66 different sequencing techniques and step-by-step NGS data analysis pipelines comparing popular tools. SequencEnG is designed to facilitate barrier-free learning of current NGS techniques and provides a user-friendly interface for searching through experimental and analysis methods. SequencEnG is part of the project KnowEnG (Knowledge Engine for Genomics) and is freely available at http://education.knoweng.org/sequenceng/.

bioinformatics↗

bioRxiv2017

ClusterEnG: An interactive educational web resource for clustering big data

SummaryClustering is one of the most common techniques used in data analysis to discover hidden structures by grouping together data points that are similar in some measure into clusters. Although there are many programs available for performing clustering, a single web resource that provides both state-of-the-art clustering methods and interactive visualizations is lacking. ClusterEnG (acronym for Clustering Engine for Genomics) provides an interface for clustering big data and interactive visualizations including 3D views, cluster selection and zoom features. ClusterEnG also aims at educating the user about the similarities and differences between various clustering algorithms and provides clustering tutorials that demonstrate potential pitfalls of each algorithm. The web resource will be particularly useful to scientists who are not conversant with computing but want to understand the structure of their data in an intuitive manner.\n\nAvailabilityClusterEnG is part of a bigger project called KnowEnG (Knowledge Engine for Genomics) and is available at http://education.knoweng.org/clustereng.\n\nContactsongi@illinois.edu

bioinformatics↗