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Biology subjects

Horii, Y.

Publications and source records attributed to Horii, Y..

3 recordsLinked to original sources

Thermal Conductivity of Artificial Materials Engineered from Plant and Bacterial Cells

Bio-based materials are known for their excellent biodegradability and, in some cases, their potential to fix carbon dioxide. Owing to these properties, they are increasingly being utilized as environmentally friendly alternatives across various applications. In this study, we focused on using living cells themselves as material components, aiming to evaluate their potential as substitutes for conventional plastic-based thermal insulators. We selected two types of cells, photosynthetic purple non-sulfur bacterium Rhodovulum sulfidophilum and tobacco BY-2 plant suspension cells. After optimizing solidification conditions through the addition of pectin and cellulose nanofibers, we measured the thermal conductivity of the solidified cells under atmospheric pressure. The results showed that R. sulfidophilum exhibited 0.0553 W/m{middle dot}K, while BY-2 exhibited a thermal conductivity of 0.043 W/m{middle dot}K. Both values indicate relatively low thermal conductivity compared to existing bio-based materials, suggesting high insulation performance. Among the solidified cells, the solidified BY-2 cells showed minimal variation in thermal insulation performance under pressure changes, and had a low thermal emissivity as revealed by FT-IR analysis. Based on these findings, we propose that cell-derived materials can serve as potentially biodegradable bio-based thermal insulation materials.

bioengineering↗

IL-18 produced by pregnant uterus promotes essential inflammatory responses and fetoplacental growth

Placental insufficiency affects fetomaternal health throughout life. Although the interaction between the maternal uterine immune milieu and fetal-derived cells plays a crucial role in placental formation, several aspects remain unclear. Therefore, we conducted this study to investigate the effects of interleukin (IL)- 18, a unique cytokine with both proinflammatory and anti-inflammatory properties, on the uterine immune milieu and placental development. Our results identified pregnant uterine smooth muscle cells as an important source of IL-18, which supports homeostatic type 1 immune responses. IL-18 facilitates appropriate placental development through uterine vascular remodeling and placental angiogenesis. Smooth muscle cell-specific Il18-knockout dam mice exhibited impaired fetoplacental growth and elevated maternal blood pressure, reflecting preeclampsia-like phenotypes. Their offspring demonstrated a tendency toward excessive weight gain and delayed neurodevelopment. Overall, this study emphasizes the essential role of IL-18 in placental formation and its wider implications for fetomaternal health. Graphical Abstract O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=200 SRC="FIGDIR/small/649615v1_ufig1.gif" ALT="Figure 1"> View larger version (40K): org.highwire.dtl.DTLVardef@27862eorg.highwire.dtl.DTLVardef@da4786org.highwire.dtl.DTLVardef@8dd7e2org.highwire.dtl.DTLVardef@584c41_HPS_FORMAT_FIGEXP M_FIG C_FIG HighlightsO_LISmooth muscle cells in the pregnant uterine myometrium sufficiently produce IL-18 C_LIO_LIIL-18 induces type 1 immune responses in the uterine immune milieu C_LIO_LIIL-18 promotes maternal uterine vascular remodeling and placental angiogenesis C_LIO_LIIL-18-signaling deficiency in the mouse model shows the preeclampsia-like clinical course C_LI

immunology↗

Efficient callus induction and completion of regeneration in kenaf Hibiscus cannabinus

Kenaf, Hibiscus cannabinus, is a fiber-enriched plant belonging to Malvaceae and is an important fiber crop. The features of kenaf of being fast-growing and fiber-enriched suggest the potential for the use of kenaf in biomass and materials; however, the complete regeneration procedure, which is essential for genetic modification, is lacking. Here, we report the complete regeneration of kenaf from cotyledon explants achieved by callus induction on an improved callus-inducing medium and shoot induction on a shoot-inducing medium and by seed setting under a regulated growth condition in a chamber. Our complete regeneration method will enable the production of stably transformed kenaf that can improve the properties of kenaf as a material.

plant biology↗