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Fotopoulou, K.

Publications and source records attributed to Fotopoulou, K..

4 recordsLinked to original sources

Gender and geographical disparity in editorial boards of journals in psychology and neuroscience

While certain metrics of diversity have seen great improvement in recent years in academic psychology and neuroscience, unequal representation remains for many positions of power. Here, we reviewed publicly available information in order to infer the proportion of editors by gender and their country of affiliation in the top 50 journals worldwide in each of the two fields. The sample included a total of 2,864 editors for psychology journals and 3,093 editors for neuroscience journals. There was a statistically significant difference in the proportion of male and female editors in both fields, both across editorial roles, and within various role categories, including editor-in-chief and their deputies at neuroscience journals, associate and section editors in both fields, and editorial and advisory board members in both fields. The only category in which there was not a significant imbalance of male and female scholars was the editors-in-chief of psychology journals and their deputies. Geographically, USA-based academics significantly outnumbered those from other countries as editors in both psychology and neuroscience. Results also indicated that over three quarters of psychology journals (76%) were comprised of more than 50% male editors, while only 20% had a similar proportion of female editors. In neuroscience, 88% of journals were comprised of more than 50% male editors, while only 10% of journals included a similar, proportional majority of female editors. Findings suggest that editorial positions in academic journals, possibly one of the most powerful decision-making roles in academic psychology and neuroscience, are not balanced in gender or geographical representation.

scientific communication and education↗

Less is more: a dose-response mechanistic account of intranasal oxytocin pharmacodynamics in the human brain

Intranasal oxytocin is receiving increasing research attention as a potential treatment for several brain disorders due to promising preclinical results. However, translating these findings to humans has been hampered by remaining uncertainties about its pharmacodynamics and the methods used to probe its effects in the human brain. Using a dose-response design (9, 18 and 36 IU) and a novel administration device, we demonstrate that oxytocin-induced physiological changes in the amygdala at rest, a key-hub of the brain oxytocin system, follow a dose-response curve with maximal effects for lower doses. Yet, the effects of oxytocin vary by amygdala subdivision, highlighting the need to qualify dose-response curves within subregion. We further link physiological changes with the density of the oxytocin receptor gene mRNA across brain regions, strengthening our confidence in intranasal oxytocin as a valid approach to engage central targets. Finally, we demonstrate that intranasal oxytocin does not disrupt cerebrovascular reactivity; the absence of major vascular confounds corroborates the validity of haemodynamic neuroimaging to probe the effects of intranasal oxytocin in the human brain.

neuroscience↗

Anosognosia for Hemiplegia as a tripartite disconnection syndrome

The rare syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural networks that contribute to AHP, when disconnected: the (1) premotor loop (2) limbic system, and (3) ventral attention network. Our results suggest that human motor awareness is contingent on the joint contribution of these three systems.

neuroscience↗

Mapping drinking water and quality of life aspects in urban settings: an application of the urban exposome

Cities face rapid changes leading to increasing inequalities and emerging public health issues that require cost-effective interventions. The urban exposome framework constitutes a novel approach in tackling city-wide challenges, such as those of drinking water quality and quality of life. In this proof-of-concept study, we presented part of the urban exposome of Limassol (Cyprus) focusing on chemical and microbial drinking water quality parameters and their association with urban neighborhood indicators. A perceptions study and an urban population study was conducted. We mapped the water quality parameters and participants opinions on city life (i.e. neighborhood life, health care and green space access) using quarters (small administrative areas) as the reference unit of the city. In an exploratory environment-wide association study analysis, we used all variables (questionnaire responses and water quality metrics) to describe correlations between them accounting, also, for self-reported health status. Overall, urban drinking-water quality using conventional indicators of chemical (disinfection byproducts-trihalomethanes) and microbial (coliforms, E. coli, and Enterococci) quality did not raise particular concerns. The general health and chronic health status of the urban participants were significantly (all >FDR corrected p value of 0.1) associated with different health conditions such as hypertension and asthma, or having financial issues in access to dental care. Additionally, correlations between trihalomethanes and participant characteristics (e.g. household cleaning, drinking water habits) were documented. This proof-of-concept study showed the potential of using integrative approaches to develop urban exposomic profiles and identifying within-city differentiated environmental and health indicators. The characterization of the urban exposome of Limassol will be expanded via the inclusion of biomonitoring tools and untargeted metabolomics platforms.

epidemiology↗