Biology subjects

Dyble, M.

Publications and source records attributed to Dyble, M..

3 recordsLinked to original sources

bioRxiv2023

Patterns of physical activity in hunter-gatherer children compared with US and UK children.

Sedentary lifestyles, mismatched with our active foraging history, contribute to escalating rates of non-communicable diseases. Contemporary hunter-gatherers appear to be highly active, but little is known about physical activity levels in hunter-gatherer children. We analysed 150 days of accelerometer data from 51 BaYaka hunter-gatherer children (aged 3-18) in the Republic of Congo, comparing it with British and American children (MCS and NHANES). BaYaka children were highly active, engaging in over 3 hours of moderate-to-vigorous physical activity (MVPA) daily, surpassing British adolescents by over 70 minutes. In US children activity declined with age; while in BaYaka children activity increased with age, unaffected by gender. Reflecting their foraging lifestyle, activity patterns varied within and between days, yet all children consistently rose with the sun. These findings highlight the impact of a foraging upbringing on childrens activity levels, providing a benchmark for understanding childhood physical activity and wellbeing.

evolutionary biology↗

bioRxiv2022

Hunter-gatherer oral microbiomes are shaped by contact network structure

Ancestral humans evolved a complex social structure still observed in extant hunter-gatherers. Here we investigate the effects of extensive sociality and mobility on the oral microbiome of 138 Agta hunter-gatherers from the Philippines. Comparisons of microbiome composition showed that the Agta are more similar to Central African Bayaka hunter-gatherers than to neighboring farmers. We also defined the Agta social microbiome as a set of 137 oral bacteria (only 7% of 1980 amplicon sequence variants) significantly influenced by social contact (quantified through wireless sensors of short-range interactions). We show that interaction networks covering large areas, and their strong links between close kin, spouses, and even unrelated friends, can significantly predict bacterial transmission networks across Agta camps. Finally, more central individuals to social networks are also bacterial supersharers. We conclude that hunter-gatherer social microbiomes, which are predominantly pathogenic, were shaped by evolutionary tradeoffs between extensive sociality and disease spread.

microbiology↗

bioRxiv2022

The making of the oral microbiome in Agta hunter-gatherers

Ecological and genetic factors have influenced the composition of the human microbiome during our evolutionary history. We analyzed the oral microbiota of the Agta, a hunter-gatherer population where part of its members is adopting an agricultural diet. We show that age is the strongest factor modulating the microbiome, likely through immunosenescence as there is an increase of pathogenicity with age. Biological and cultural processes generate sexual dimorphism in the oral microbiome. A small subset of oral bacteria is influenced by the host genome, linking host collagen genes to bacterial biofilm formation. Our data also suggests that shifting from a fish/meat to a rice-rich diet transforms their microbiome, mirroring the Neolithic transition. All these factors have implications in the epidemiology of oral diseases. Thus, the human oral microbiome is multifactorial, and shaped by various ecological and social factors that modify the oral environment.

microbiology↗