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Dandin, M.

Publications and source records attributed to Dandin, M..

2 recordsLinked to original sources

Capacitance Sensor Array for Lab-on-CMOS Applications using a Passive RFID Interface

We report a 0.18 {micro}m CMOS lab-on-a-chip system that monolithically integrates a passive radio frequency identification (RFID) interface and an 8 x 8 array of capacitance sensors configured for measuring the capacitance change resulting from an overlying biological specimen. This lab-on-CMOS platform is designed to operate wirelessly, first in a harvesting mode in which on-chip power is generated via the inductive coupling of an on-chip antenna to an external antenna, and second, in a sense-and-transmit mode where the capacitance sensor array is scanned and the measured data are transmitted to the external antenna using the same on-chip antenna. This paper presents characterization results of the passive RFID interface and of the sensor core, the latter utilizing several test analytes. The proposed system will facilitate the integration and packaging of a large number of chips in wet environments, paving the way for the inclusion of lab-on-CMOS technology in standard bio-analytical lab practice.

bioengineering↗

Measuring and Modeling Macrophage Growth using a Lab-on-CMOS Capacitance Sensing Microsystem

We report on the use of a lab-on-CMOS biosensor platform for quantitatively tracking the growth of RAW 264.7 murine Balb/c macrophages. We show that macrophage growth over a wide sensing area correlates linearly with an average capacitance growth factor resulting from capacitance measurements at a plurality of electrodes dispersed in the sensing area. We further show a temporal model that captures the cell evolution in the area of interest over long periods (e.g., 30 hours). The model links the cell numbers and the average capacitance growth factor associated with the sensing area to describe the observed growth kinetics.

bioengineering↗