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Cornwell, T. I.

Publications and source records attributed to Cornwell, T. I..

2 recordsLinked to original sources

Proactive adjustments to cued gait perturbations in people with and without chronic stroke

Balance disturbances exist along a continuum from those that are fully unexpected to those that are predictable based on cues from the environment. When people experience predictable disturbances while walking, they may proactively adjust their gait to minimize losses of balance. However, ones ability to effectively implement these proactive control strategies may be impaired after a stroke due to a combination of motor and cognitive impairments that result from brain lesions. Here, we used explicit audiovisual cues to characterize the proactive and reactive control strategies implemented by people with and without stroke during unexpected versus expected gait perturbations. Following unexpected treadmill accelerations, both groups had smaller margins of stability on the recovery step than during unperturbed walking. When we provided audiovisual cues specifying the impending perturbation step, people without stroke performed less leg and joint work, especially at the ankle, during the cued perturbations and increased their subsequent margins of stability by approximately 3 cm on the recovery step. However, people post-stroke did not make the same proactive adjustments. Instead, after any perturbation, they modified their stepping to maintain their center of mass position within their base of support, and this strategy remained unchanged with audiovisual cues. Our findings suggest that people post-stroke rely on a general control strategy rather than proactively modifying push-off work, even when given precise timing information about the impending gait perturbations.

physiology↗

Stroke impairs the proactive control of dynamic balance during predictable treadmill accelerations

We maintain balance during gait using both proactive and reactive control strategies. Damage to the brain from a stroke impairs reactive balance, but little is known about how a stroke impacts proactive control during walking. Stroke-related impairments to proactive control could become targets for interventions designed to improve responses to predictable disturbances and reduce fall risk. Therefore, we determined if proactive strategies during predictable treadmill accelerations differed between people post-stroke (n=14) and people without stroke (n=14). Both groups walked with accelerations at random (every one to five strides) and regular (every three strides) intervals. We quantified the effects of the perturbations as changes to center of mass (COM) speed and used mechanical leg work to quantify the proactive strategies to slow the COM. Participants without stroke reduced peak COM speed better than those with stroke when perturbations were regular (-0.016 versus +0.004 m/s; p=0.007). They also reduced positive leg work more during the perturbation step than the group post-stroke (-5.7% versus +2.5%; p=0.003). One implication of these findings is that people post-stroke may be more susceptible to falls during predictable gait disturbances, and future work should identify the underlying impairments that cause these deficits.

physiology↗