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Caballero Perez, J.

Publications and source records attributed to Caballero Perez, J..

2 recordsLinked to original sources

Databiology Lab CORONAHACK: Collection of Public COVID-19 Data

COVID-19 has had an unprecedented global impact in health and economy affecting millions of persons world-wide. To support and enable a collaborative response from the global research communities, we created a data collection for different public sources for anonymized patient clinical data, imaging datasets, molecular data as nucleotide and protein sequences for the SARS-CoV-2 virus, reports of count of cases and deaths per city/country, and other economic indicators in Databiology Lab (https://www.lab.databiology.net/) where researchers could access these data assets and use the hundreds of available open source bioinformatic applications to analyze them. These data assets are regularly updated and was used in a successful virtual 3-day hackathon organized by Databiology Ltd and Mindstream-AI where hundreds of attendees to work collaboratively to analyze these data collections.

bioinformatics

Overview of the expression of key regeneration genes in embryo development and matured tissues in Axolotl (Ambystoma mexicanum)

The axolotl is a Mexican endangered species with the capability to perform tissue regeneration in amputated extremities. Being an important research model, the complete genome of the Axolotl was sequenced in 2018 for the first time, revealing an enormous genome: the largest of any animal ever sequenced, and about 10 times larger than the human genome, a new landmark achievement in biology research. In this report, we collected 70 known genes that play an important role in tissue regeneration and searched for their expression during embryo development, regeneration, and in 6 adult tissues: the heart, liver, gills, front leg, rear leg, and tail. We observe those 70 genes expression levels in the 3 conditions and approximately 3 genes seem to be expressed exclusively in regeneration. This report displays a few insights on how this marvelous species can modulate its regenerative capabilities. There is still much more to explore with the Axolotl. Further research into their regenerative capabilities could provide researchers with the perspicacity to possibly accomplish human limb regeneration.

molecular biology