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Biology subjects

Bemrose, M. A.

Publications and source records attributed to Bemrose, M. A..

2 recordsLinked to original sources

TweetyBERT: Automated parsing of birdsong through self-supervised machine learning.

Deep neural networks can be trained to parse animal vocalizations - serving to identify the units of communication, and annotating sequences of vocalizations for subsequent statistical analysis. However, current methods rely on human labelled data for training. The challenge of parsing animal vocalizations in a fully unsupervised manner remains an open problem. Addressing this challenge, we introduce TweetyBERT, a self-supervised transformer neural network developed for analysis of birdsong. The model is trained to predict masked or hidden fragments of audio, but is not exposed to human supervision or labels. Applied to canary song, TweetyBERT autonomously learns the behavioral units of song such as notes, syllables, and phrases - capturing intricate acoustic and temporal patterns. This approach of developing self-supervised models specifically tailored to animal communication will significantly accelerate the analysis of unlabeled vocal data.

animal behavior and cognition↗

Direct laser writing of 3D electrodes on flexible substrates

This report describes a 3D microelectrode array integrated on a thin-film flexible cable for neural recording in small animals. The micro electrode array fabrication process integrates traditional silicon thin-film processing techniques and direct laser writing of 3D structures at micron resolution via two-photon lithography. While direct laser writing of 3D printed electrodes has been described before, this report is the first to provide a method for high-aspect-ratio laser-written structures integrated with microfabricated electrical traces. One prototype is a 16-channel array composed of 350 m long shanks spaced on a grid with 90 m pitch. Other devices shown here include biomimetic mosquito-needles that penetrate through the dura of birds and porous electrodes designed to promote tissue ingrowth or enhance charge injection capacity for neural stimulation. These devices are just a few examples of a new design space that will enable high-channel-count 3D electrode arrays with features definable at single micrometer resolution. Using a custom laser writer, the 3D printing process is rapid (1 mm3/min). This high-speed printing combined with standard wafer-scale processes will enable efficient device fabrication and new studies examining the relationship between electrode geometry and electrode performance. We anticipate highest impact in small animal models, nerve interfaces, retinal implants, and other applications requiring small, high density 3D electrodes.

bioengineering↗