ascend: R package for analysis of single cell RNA-seq data
Summaryascend is an R package comprised of fast, streamlined analysis functions optimized to address the statistical challenges of single cell RNA-seq. The package incorporates novel and established methods to provide a flexible framework to perform filtering, quality control, normalization, dimension reduction, clustering, differential expression and a wide-range of plotting. ascend is designed to work with scRNA-seq data generated by any high-throughput platform, and includes functions to convert data objects between software packages.\n\nAvailabilityThe R package and associated vignettes are freely available at https://github.com/IMB-Computational-Genomics-Lab/ascend.\n\nContactjoseph.powell@uq.edu.au\n\nSupplementary informationAn example dataset is available at ArrayExpress, accession number E-MTAB-6108