Almeida Villegas, J. A. | bioRxiv Science

bioRxiv2020

Resistance to different antibiotics in clinical isolates of Enterococcus faecalis obtained from urine cultures of patients with urinary tract infection

ObjectiveTo identify patterns of resistance against various antibiotics in Enterococcus faecalis in urinary tract infections in a population of the Toluca valley, Mexico Methods155 samples were collected from patients with suspected urinary tract infection without exclusion criteria such as age or gender. Automated equipment was used for the identification of the etiological agent and sensitivity tests. Results80 positive cultures were obtained, of which 20 strains belong to Enterococcus faecalis, which show 100% sensitivity for penicillins, linezolid, vancomycin, bacitracin, a high pattern of sensitivity for quinolones, and a high pattern of resistance to rifampicin, erythromycin and 100% resistance in tetracycline ConclusionIt shows 100% sensitivity to penicillins, vancomycin and linezolid, first-line treatments and for cases of infection complicated by Enterococci. And 100% resistance for tetracycline and high resistance patterns for erythromycin and rifampin.

microbiology↗

bioRxiv2020

Quinolone resistance in different uropathogens isolated from urine cultures in patients with urinary tract infection

ObjectiveTo identify patterns of resistance against quinolones in various uropathogens in urinary tract infections in the population of the Toluca valley, Mexico IntroductionQuinolones are antibiotics with a spectrum of activity for both gram-positives and gram-negatives and are antibiotics used for the empirical treatment of urinary tract infections. Recently, a high index of resistance to quinolones has been reported due to different mechanisms on the part of bacteria, however the one that has taken the greatest importance is the presence of extended spectrum beta-lactamases Methods155 samples were collected from patients with suspected urinary tract infection without exclusion criteria such as age or gender. Automated equipment was used for the identification of the etiological agent and sensitivity tests to quinolones. ResultsThe results positives were divided to evaluate which of the two antibiotics studied had greater resistance. For ciprofloxacin there are 27 resistant strains 37%, 1 strain with intermediate resistance 1% and 45 susceptible strains 62%. For levofloxacin 26 strains are resistant 36%, 41 strains are sensitive 56% and 6 strains show intermediate sensitivity 8%. ConclusionDifferent microorganisms, both gram-positive and gram-negative, were isolated and it can be observed that gram-negative strains are the ones with the greatest resistance against quinolones, mainly Escherichia coli, which produces extended-spectrum beta-lactamases, in the case of gram-positive resistance patterns are variable with a tendency towards sensitivity.

microbiology↗