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Aitchison, L.

Publications and source records attributed to Aitchison, L..

2 recordsLinked to original sources

Unifying error and reward action learning: a cerebello-basal ganglia theory

Learning depends on both reward- and error-based feedback, yet how the brain integrates these distinct signals to guide behaviour remains fundamentally unclear. Here, using a normative computational framework, we derive credit assignment rules for both reward-based learning (RBL) and error-based learning (EBL). In contrast to existing dual-policy accounts, our approach demonstrates that RBL and EBL updates can be reformulated into a shared action-gradient space that directly updates a single downstream policy. First, we map this action-gradient framework onto a systems-level account of coordinated interactions between the basal ganglia, cerebellum, and cortex. The model reproduces key behavioral features across both learning regimes, generates experimentally testable predictions, and provides a unified computational account of motor deficits observed in patients with cerebellar and basal ganglia disorders. Together, our work offers a normative, brain-wide framework for how distributed brain systems integrate reinforcement and error-driven feedback toward a common behavioral objective.

neuroscience↗

Cortical-like dynamics in recurrent circuits optimized for sampling-based probabilistic inference

Sensory cortices display a suite of ubiquitous dynamical features, such as ongoing noise variability, transient overshoots, and oscillations, that have so far escaped a common, principled theoretical account. We developed a unifying model for these phenomena by training a recurrent excitatory-inhibitory neural circuit model of a visual cortical hypercolumn to perform sampling-based probabilistic inference. The optimized network displayed several key biological properties, including divisive normalization, as well as stimulus-modulated noise variability, inhibition-dominated transients at stimulus onset, and strong gamma oscillations. These dynamical features had distinct functional roles in speeding up inferences and made predictions that we confirmed in novel analyses of awake monkey recordings. Our results suggest that the basic motifs of cortical dynamics emerge as a consequence of the efficient implementation of the same computational function--fast sampling-based inference--and predict further properties of these motifs that can be tested in future experiments.

neuroscience↗